RCT characteristics
The database includes a total of 432 RCTs from 42 different countries. These RCTs were published in 153 different journals in 8 languages between 1986 and 2019.
| Trial characteristics | Results |
|---|---|
| Design | - |
| Pilot trial | 65 of 432 (15.0%) |
| Medication intervention | 240 of 432 (55.6%) |
| Blinding reported | 214 of 432 (49.5%) |
| High risk of bias | 212 of 432 (49.1%) |
| Centres | - |
| Multicentred | 80 of 432 (18.5%) |
| Number of centres in multicentred | 5 (2, 15) min=2 max=104 n=80 |
| Countries | - |
| Multinational | 29 of 432 (6.7%) |
| International collaboration | 70 of 432 (16.2%) |
| Funding | - |
| Any funding reported | 216 of 432 (50.0%) |
| Any commercial funding reported | 47 of 432 (10.9%) |
| Results | - |
| Total children randomized | 51941 |
| Children randomized per RCT | 56 (36, 101.5) min=6 max=4947 n=431 |
| Children analyzed | 50.5 (32.8, 100) min=6 max=4947 n=412 |
| Stopped early | 60 of 230 (26.1%) |
| Results statistically significant | 105 of 259 (40.5%) |
| Impact | - |
| Journal impact factor | 3 (2.1, 7) min=0.2 max=70.7 n=385 |
| Citations per year | 1.8 (0.6, 3.6) min=0 max=44.6 n=418 |
Children randomized per RCT
The solid red line shows the overall median number of children randomized per RCT and the dashed red lines show the 1st and 3rd quartile.
Types of interventions tested
The area of each block is proportional to the number of RCTs in that category. The number in parentheses is the number of RCTs in that category.
Indication for interventions tested
The area of each block is proportional to the number of RCTs in that category. The number in parentheses is the number of RCTs in that category.
Population studied
The area of each block is proportional to the number of RCTs in that category. The number in parentheses is the number of RCTs in that category.
Report generated: 13-Sep-19 at 15:01h
Database version: 2019Q2
Date of last searches: 02-Jul-19