RCT characteristics
The database includes a total of 415 RCTs from 41 different countries. These RCTs were published in 148 different journals in 8 languages between 1986 and 2018.
| Trial characteristics | Results |
|---|---|
| Design | - |
| Pilot trial | 60 of 415 (14.5%) |
| Medication intervention | 232 of 415 (55.9%) |
| Blinding reported | 206 of 415 (49.6%) |
| High risk of bias | 202 of 415 (48.7%) |
| Centres | - |
| Multicentred | 78 of 415 (18.8%) |
| Number of centres in multicentred | 5.5 (2, 15) min=2 max=104 n=78 |
| Countries | - |
| Multinational | 28 of 415 (6.7%) |
| International collaboration | 66 of 415 (15.9%) |
| Funding | - |
| Any funding reported | 207 of 415 (49.9%) |
| Any commercial funding reported | 46 of 415 (11.1%) |
| Results | - |
| Total children randomized | 49721 |
| Children randomized per RCT | 55 (35, 101) min=6 max=4947 n=415 |
| Children analyzed | 50 (32, 100) min=6 max=4947 n=397 |
| Stopped early | 58 of 218 (26.6%) |
| Results statistically significant | 100 of 249 (40.2%) |
| Impact | - |
| Journal impact factor | 3.2 (2.3, 6.6) min=0.2 max=79.3 n=369 |
| Citations per year | 1.8 (0.6, 3.4) min=0 max=43.4 n=401 |
Children randomized per RCT
The solid red line shows the overall median number of children randomized per RCT and the dashed red lines show the 1st and 3rd quartile.
Types of interventions tested
The area of each block is proportional to the number of RCTs in that category. The number in parentheses is the number of RCTs in that category.
Indication for interventions tested
The area of each block is proportional to the number of RCTs in that category. The number in parentheses is the number of RCTs in that category.
Population studied
The area of each block is proportional to the number of RCTs in that category. The number in parentheses is the number of RCTs in that category.
Report generated: 26-Feb-19 at 15:50h
Database version: 2018Q4
Date of last searches: 04-Jan-19